Problems of serial cardiac output determinations in human volunteers

The normal resting cardiac output: serial determinations by a dye dilution method.

The resting output of the normal heart has been investigated by many workers (Krogh and Lindhard, 1912; Christiansen et al., 1914; Stewart, 1921; Grollman, 1928; Hamilton et al., 1932; Nylin, 1933; Berseus, 1943; McMichael and Sharpey-Shafer, 1944; Cournand et al., 1945; Stead et al., 1945; Werko, 1947; Chapman et al., 1950; Doyle, et al., 1953; Donald et al., 1955; Goodyer et al., 1960; Reeves...

Serial Cardiac Output and Blood Volume Studies Following Cardiac Valve

DETERMINATION of the cardiac output during the early postoperative period following open heart surgery has been difficult due to technical problems in adapting the Fick and indicator-dilution methods to the bedside. The recent availability of a radioisotopedilution method using precordial detection provides a simple and reliable means of measuring blood flow in the postoperative setting. In add...

Validity of indicator-dilution determinations of cardiac output in patients with mitral regurgitation.

mHE indicator-dilution method has been widely employed for determination of cardiac output since its introduction by Stewart' and Hamilton and associates.2 The effect of unrecognized recirculation of indicator particles upon the primary indicator time-concentration curve has caused concern as to whether this method may be employed in such conditions as mitral regurgitation3' 4and as to whether ...

Serial determinations of blood lactate in respiratory distress syndrome.

Serial determinations of oxygen profiles in infants with respiratory distress.

Serial oxygen profiles were determined for 20 newborn infants by measuring arterial tensions at low (20--40%), intermediate (60--80%), and high (95--100%) levels of inspired oxygen. These points were plotted on a graph which estimated the percentage of venous admixture at any particular level of inspired oxygen. The infants' oxygen profiles were then determined. As much as 25% of venous admixtu...